99% Purity CAS 70288-86-7 Ivermectin Veterinary Ivermectin Raw Material Powder Ivermectin
Product Description
| Product name |
Ivermectin Powder |
| Purity |
99% |
| Appearance |
White powder |
| CAS |
70288-86-7 |
| Molecular Formula |
C48H74O14 |
| Formula Weight |
875.09 |
Ivermectin is a new type of broad-spectrum, high-efficiency, low-toxicity antibiotic antiparasitic drug, which has a good repellent effect on internal and external parasites, especially nematodes and arthropods. But it has no effect on tapeworms, flukes and protozoa. The repellent effect of macrolide antiparasitic drugs on nematodes and arthropods is to increase the release of the inhibitory transmitter γ-aminobutyric acid (GABA) and to open the Cl ion channel controlled by glutamate. Enhance the permeability of the nerve membrane to Cl, thereby blocking the transmission of nerve signals, and eventually nerve paralysis, causing muscle cells to lose the ability to contract, which leads to the death of the worm.
(1)Ivermectin is widely used in gastrointestinal nematodes, lung nematodes and parasitic arthropods of cattle, sheep, horses and pigs, intestinal nematodes of dogs, ear mites, scabies, heartworms and microfilaria, and poultry stomachs Intestinal nematodes and ectoparasites.
(L) Bovine and sheep ivermectin is administered orally or subcutaneously to cattle and sheep at 0.2 mg/kg, against Haemonchus, Oersted nematode, Cooper nematode, Trichostrongylus elegans (including Trichostrongylus elhii) , Round nematodes, larval nematodes, thinneck nematodes, Trichinella spiralis, esophageal mouth nematodes, Dictyostelium nematodes and sheep Shabot nematode adults and the fourth stage larvae, the deworming rate is 97%-100%. The above doses are also very effective for arthropods: such as fly maggots (bovine flies, striated skin flies, sheep fly), mites (bovine scabies, sheep itch mites) and lice (bovine palate louse, bovine blood louse and sheep palate louse) Wait. Ivermectin is slightly less effective for chewing lice (Trichodesma) and sheep tick flies.
(2) Oral administration of 0.2 mg/kg ivermectin for horses and horses is highly effective (95% to 100%) for the following adult and fourth stage larvae of large and small round nematodes; such as large round nematodes (normal round nematodes) Nematodes, horse circle nematode, adentate circle nematodes), roundworms (Parascaris equine), pinworms (equine worms), gastric worms (Draschia grandis, genus Nematodes), small intestine nematodes (Erinda Trichostrongylus, Strongyloides Wechneri), Pulmonary Nematodes (Dictychus Andrii), etc. For the three kinds of horse stomach fly maggots in the migration or gastric residence period, the onchocerciae microfilaria that cause skin damage, and the third stage larvae of gastric nematodes, although the amount of 0.2mg/kg at one time is very limited, but the best solution One month later, the above-mentioned dose was given again.
(3) Pigs Intramuscular injection of 0.3mg/kg ivermectin has broad-spectrum anthelmintic activity on pigs. Such as Ascaris suum, Strongyloides rubrum, Strongyloides lanceolata, Trichoderma suis, Nematodes of the esophagus, Metastrongylus, Coronaria dentata, adult and immature worms, the extermination rate reaches 94%-100%. Trichinella in the tract (ineffective in muscle) is also extremely effective. The above-mentioned medication method also has a good control effect on swine blood lice and swine scabies mites.
(4) Dogs and cats have special formulations abroad (at 6-12μg/kg) for the prevention and treatment of heartworm microfilaria infection in dogs. In my country, 50μg/kg oral administration can be tried to treat heartworm microfilaria infection (adults). invalid). Clinical trials have confirmed that high-dose ivermectin is highly effective against a variety of dog parasites, such as a subcutaneous injection of 50μg/kg for Ancylostoma canis, Ancylostoma brasiliensis, Ancylostoma canis, and 100 μg/kg against Trichuris canis , 200μg/kg has an excellent repellent effect on Toxoplasma canis adult and fourth stage larvae. For Toxoplasma lionii, according to the amount of 200μg/kg, the curative effect of subcutaneous injection is only 69%, while that of oral administration is 95%. This product is injected subcutaneously once to treat dogs with parasitic capillaries (200μg/kg) and Ossler's nematode (400μg/kg) in the lungs of dogs.
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