Pharmaceutical Grade CAS 15663-27-1 Cisplatin Antitumor Cisplatin Powder Cisplatin

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Cisplatin
• Product Name: Cisplatin
• Name: Cisplatin Powder
• Appearance: Yellow Powder
• Color: Yellow
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 15663-27-1
• Mf: Cl2h6n2PT
• MW: 300.05
• Melting Point: 270 C
• Storage Temperature: Room Temp
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 1000kg/Month

Product Description

Pharmaceutical Grade CAS 15663-27-1 Cisplatin Antitumor Cisplatin Powder Cisplatin

Product Description

Product Details

 

Name	Cisplatin
Appearance	Yellow powder
Cas number	15663-27-1
MF	Cl2H6N2Pt
MW	300.04504

This product is a heavy metal complex center at two price of platinum with two atoms and two ammoniamolecule, similar to the bifunctional alkylating agent, can inhibit the DNA replication process. The most sne DDP cells, high concentrations inhibit RNA and protein synthesis. The lack of effect of oxygen cells, into the human body can diffuse through the cell membrane charged. At present, the main site of DDP in DNA of the purine and pyrimidine bases. Effect: This product is a cell cycle non-specific drugs, has the cell toxicity, the process of DNA replication can inhibit cancer cells, and damage to the cell membrane structure, a broad-spectrum anticancer role.

Application&Function

Function
Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The compound has also been shown to induce apoptosis through caspase-3 activation and XIAP expression. Also shown to cause immunosuppression which is thought to be followed by an increase in the host immune response. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I by camptothecin (sc-200871). Cisplatin was the first member of a class of anticancer drugs, which now include carboplatin (sc-202093) and oxaliplatin (sc-202270), that form DNA adducts resulting in apoptosis; however, these molecules also bind other biological molecules such as enzymes which might play a role in their mechanism of action. 
Application
Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II)  is a platinum-based chemotherapydrug used to treat various types of cancers, including sarcomas, somecarcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, andgerm cell tumors.It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis (programmed cell death).

Specification