Antiemetic Granisetron HCl material Granisetron Powder Granisetron
Product Description
Product Datails
Product name |
Granisetron Hcl |
Appearance |
White powder |
CAS |
107007-99-8 |
MF |
C18H25ClN4O |
MW |
312.417 |
Granisetron Hcl is a highly selective 5-HT3 receptor antagonist with good preventive and therapeutic effects on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Factors such as radiotherapy, chemotherapy and surgery can cause enterochromaffin cells to release 5-HT, and 5-HT can activate 5-HT3 receptors in the central or vagus nerve and cause gag reflex. The mechanism of this product to control nausea and vomiting is to inhibit the occurrence of nausea and vomiting by antagonizing the 5-HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings. This product has high selectivity and no adverse reactions such as extrapyramidal reactions and excessive sedation.
Application&Function
Granisetron Hcl is suitable for the prevention and treatment of nausea and vomiting caused by tumor radiotherapy and chemotherapy.
Specification