Pharmaceutical Grade Fasudil 99% Purity Fasudil Powder Raw Material Fasudil

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung-Fasudil
• Product Name: Fasudil
• Name: Fasudil Powder
• Appearance: White Powder
• Color: White Color
• Store: Cool and Dry
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anthelmintics
• Specific: COA
• Test Method: HPLC, UV
• Shelf Life: 2 Years
• CAS No.: 105628-07-7
• Mf: C14h18cln3o2s
• Boiling Point: 506.2 C at 760 Mmhg
• Melting Point: 220.5 MP 219.3
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 5000kg/Month

Product Description

Pharmaceutical Grade Fasudil 99% Purity Fasudil powder Raw material Fasudil

Product Description

Product Details

Product Name	Fasudil
Appearance	White Powder
CAS No.	105628-07-7
MF	C14H18ClN3O2S

Fasudil is a cell-permeable, selective ROCK inhibitor which induces neuroprotection in vitro. Studies suggest that when acting as a ROCK inhibitor, Fasudil reduces neutrophil transendothelial migration by diminishing cytoskeletal rearrangement of endothelial cells. In addition, Fasudil significantly protects against MeHg-induced axonal degeneration and apoptotic cell death in cultured cortical neurons. Alternate studies show that Fasudil plays an important role in osteoblastic differentiation of stromal cells via increasing the mRNA expression of collagen-I, osteocalcin, and bone morphogenetic protein-2 (BMP-2). Furthermore, noggin, a BMP-2 antagonist can reverse the effects of Fasudil induced mRNA expression of collagen-I and osteocalcin. Upon inhibition of Rho-kinase. Fasudil, Monohydrochloride Salt is an inhibitor of cGKI, MSK1, PKA, PRK2, Rock-2,CaMKII, Polycystin-1 and Rsk-1.

Application&Function

Fasudil is a new with a wide range of pharmacological effects, developed by Asahi Kasei Corporation (Japan.) It is a cardiovascular and cerebrovascular which improves symptoms of ischemic cerebrovascular disease such as cerebral vasospasm following subarachnoid hemorrhage. It has significant neuroprotective and therapeutic effects for ischemic cerebrovascular disease, and is suited for clinical use, particularly at the grassroots level to reduce mortality and improve quality of life. 

Specification