99% Pure CAS 1197958-12-5 Brigatinib Pharmaceutical Brigatinib Powder Raw Materials Brigatinib

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Model NO.: D-Sung Brigatinib
• Product Name: Brigatinib
• Name: Brigatinib Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anthelmintics
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAD No.: 1197958-12-5
• Mf: C26h34cln6o2p
• Boiling Point: 737.6-70.0
• Density: 1.29-0.1 g/cm3
• Stored Temperature: 2-8 C
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 500kg/Month

Product Description

99% Pure CAS 1197958-12-5 Brigatinib Pharmaceutical Brigatinib Powder Raw Materials Brigatinib

Product Description

Product Details

Product Name	Brigatinib
Appearance	White Powder
CAD No.	1197958-12-5
MF	C26H34ClN6O2P

Brigatinib is a kinase inhibitor used to treat patients with intermittent lymphoma kinase(ALK) positive metastatic non-small cell lung cancer(NSCLC), or to tolerate crizotinib.

Application&Function

Brigatinib, also known as AP-26113, is an orally active, potent and selective Dual ALK/EGFR inhibitor. AP26113 binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells. In addition, AP26113 appears to overcome mutation-based resistance. ALK belongs to receptor superfamily and plays an important role in nervous system development; ALK dysregulation and gene rearrangements are associated with a series of tumors. EGFR is overexpressed in a variety of cancer cell types.

Specification