CAS 61337-67-5 Antidepressant Mirtazapine Purity Mirtazapine Powder Raw Powder Mirtazapine

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Mirtazapine
• Product Name: Mirtazapine
• Name: Mirtazapine Powder
• Appearance: White Crystalline Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Antidepressant
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 61337-67-5
• Mf: C17h19n3
• MW: 265.35286
• Melting Point: 114-116 Oc
• Density: 1.22
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 500kg/Month

Product Description

CAS 61337-67-5 Antidepressant Mirtazapine Purity Mirtazapine Powder Raw Powder Mirtazapine

Product Description

Product Details

Product name	Mirtazapine
Cas number	61337-67-5
Apperance	White crystalline powder
MF	C17H19N3
MW	265.35286

Mirtazapine is an atypical antidepressant with noradrenergic and specific serotonergic activity. It blocks the α2 adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizes the 5-HT2 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor but may increase serotonin and norepinephrine by other mechanisms of action.
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) introduced by Organon International in the United States in 1996, and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA) and is the 6-aza analogue of mianserin. It is also racemic-occurs as a combination of both (R)-(−)- and (S)-(+)-stereoisomers, both of which are active.

Mirtazapine is a potent tetracyclic antidepressant.Target: 5-HT ReceptorMirtazapine, the novel antidepressant, has a dual mode of action. It is a noradrenergic and specific serotonergic antidepressant (NaSSA) that acts by antagonizing the adrenergic alpha2-autoreceptors and alpha2-heteroreceptors as well as by blocking 5-HT2 and 5-HT3 receptors.Mirtazapine appears to have a substantial ameliorating effect on hot flushes and perspiration bouts. It is postulated that the 5-HT(2A) blocking properties of mirtazapine is accounted in the symptomatic relief of hot flushes. After 4-24 weeks of treatment, mirtazapine induced downregulation of platelet alpha(2A)-adrenoceptors (up to 34%) and Galphai proteins (up to 28%), and the upregulation of GRK 2 (up to 30%). Treatment with mirtazapine reversed this abnormality and induced downregulation of alpha(2A)-adrenoceptor/Galphai complex.

Application&Function

Mainly used to treat all kinds of depression. It is effective for symptoms such as anhedonia, psychomotor depression, poor sleep (early awakening), and weight loss. It can also be used for other symptoms such as loss of interest in things, suicidal thoughts, and mood swings (good morning, bad night). This medicine takes effect after 1-2 weeks of administration.

Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance.

Specification