Pharmaceutical CAS 112828-00-9 Calcipotriol Compound Calcipotriol Powder Calcipotriol

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Calcipotriol
• Product Name: Calcipotriol
• Name: Calcipotriol Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Treatment Psoriasis
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 112828-00-9
• Mf: C27h40o3
• MW: 412.60500
• Boiling Point: 582ºC at 760 Mmhg
• Density: 1.12 g/cm3
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 500kg/Month

Product Description

Pharmaceutical CAS 112828-00-9 Calcipotriol Compound Calcipotriol Powder Calcipotriol

Product Description

Product Details

Product name	Calcipotriol
Appearance	White powder
CAS NO.	112828-00-9
MF	C27H40O3
MW	412.60500

Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.

Calcipotriol is a topical vitaminD3 derivative effective in the treatment of psoriasis vulgaris. The drug acts by binding to vitamin D3 receptors in the skin keratinocytes, producing an elevation in cell differentiation and a reduction in cell proliferation. Although its efficacy is comparable to calcitriol, calcipotriol exhibits at least 100 times less effect on calcium metabolism in rats.

Application&Function

Calcipotriol (INN) or calcipotriene (USAN) is a synthetic derivative of calcitriol or vitamin D. It is used in the treatment of psoriasis, marketed under the trade name "Dovonex" in the United States, "Daivonex" outside of North America, and "Psorcutan" in Germany. This medication is safe for long term application in psoriatic skin condition.

Specification