| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Kanamycin |
| Appearance | White Powder |
| CAS No. | 59-01-8 |
| MF | C18H36N4O11 |
| MW | 484.5 |
Kanamycin has a strong antibacterial effect on gram-negative bacteria such as Escherichia coli, Salmonella, Klebsiella pneumoniae, Proteus mirabilis, Pasteurella, etc. It is also effective against Staphylococcus aureus, Mycobacterium tuberculosis, and Aspergillus. But it is ineffective against Pseudomonas aeruginosa, anaerobic bacteria, and other Gram positive bacteria except for Staphylococcus aureus. It is mainly used for respiratory and urinary tract infections, sepsis, mastitis, etc. caused by most Gram negative bacteria and some drug-resistant Staphylococcus aureus. It is orally administered for intestinal infections such as chicken dysentery, typhoid fever, paratyphoid fever, avian cholera, livestock and poultry colibacillosis, etc. It also has a certain effect on chronic respiratory diseases in chickens, wheezing diseases and atrophic rhinitis in pigs, as well as red neck disease in turtles and diseases of famous and excellent aquatic products.
Intramuscular injection of 0.5g resulted in a peak blood concentration of approximately 20 μ g/ml within 1 hour, with a t1/2 of approximately 2.5 hours. The plasma protein binding rate was very low, with a distribution volume (Vd) of 0.26 ± 0.05L/kg. Within 24 hours after administration, 90% of the drug was excreted in its original form from the urine. This product is prone to penetrate pleural and ascites. Cannot reach effective concentration in cerebrospinal fluid.
Oral administration is used to treat intestinal infections caused by sensitive bacteria and to prepare for intestinal surgery. It also has the effect of reducing the production of intestinal bacteria and has a certain preventive effect on hepatic coma in patients with liver cirrhosis and gastrointestinal bleeding.
Intramuscular injection is used for systemic infections caused by sensitive bacteria, such as pneumonia, sepsis, urinary tract infections, etc.
Diluted to a certain concentration of kanamycin, sprayed on cotton leaves, can be used to identify whether it is transgenic Bt insect resistant cotton. If the leaves turn yellow, they are not resistant to cotton bollworm, and if they do not change color, they are insect resistant cotton
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