99% Purity Gliclazide Tablet Raw Material Powder Gliclazide Pharmaceutical Intermediate Gliclazide

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: Dsung-Gliclazide
• Product Name: Gliclazide
• Name: Gliclazide Powder
• Appearance: White Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediate
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 21187-98-4
• Mf: C15h21n3o3s
• MW: 323.41054
• Einecs No.: 244-260-5
• Density: 1.35
• Melting Point: 163-169 C
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 5 Ton/Month

Product Description

99% Purity Gliclazide Tablet Raw Material Powder Gliclazide Pharmaceutical Intermediate Gliclazide

 

Product Description

Product Details

Product Name	Gliclazide
CAS No.	21187-98-4
MF	C15H21N3O3S
MW	323.41054
Appearance and shape	White powder

Gliclazide, molecular formula C15H21N3O3S, is a sulfonylurea oral anti diabetes drug. It is white crystal or crystalline powder, odorless, tasteless, and used to treat type II diabetes, and β Cell sulfonylurea receptor (SUR1) binds and further blocks ATP sensitive potassium channels. Therefore, the outflow of potassium is significantly reduced, resulting in β Cell depolarization. then, β Voltage dependent calcium channels in cells open, leading to the activation of calmodulin, which leads to exocytosis containing in-sulin secretion granules. It can also effectively improve the antioxidant status and nitric- oxide mediated vasodilation in patients with type 2 diabetes, and protect the pancreas β Cells are protected from hydr ogen peroxide damage.

Application & Function

Function
Gliclazide is a 2nd generation oral sulfonylurea hypoglycemic agent with strong action.    Its mechanism is similar to that of toluenosulfonylurea, i.e., it selectively acts on pancreatic β-cells to promote insulin secretion and enhance insulin release after eating glucose, which can not only improve the metabolism of diabetic patients, but also improve or delay the occurrence of diabetic vascular complications.
Application
1.  For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.
2.  Hypoglycemic agents.  It can be used for the treatment of non- dependent diabetes mellitus.
3.  Hypoglycemic agents, non-dependent diabetes mellitus.

Specification