| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product name | Chloramphenicol |
| Appearance | White Powder |
| CAS | 56-75-7 |
| MF | C11H12Cl2N2O5 |
Usage Chloramphenicol is unusual nitroaromatic metabolite produced by Streptomyces venezuelae, first published in 1947. Chloramphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Although restricted to ocular use, antibiotic resistance to other classes has refocused attention on this class. Chloramphenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Chloramphenicol has been extensively studied with over 35,000 literature citations.
Usage Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
Mainly used in typhoid, paratyphoid fever and other salmonella, bacteroides fragilis infection. And ampicillin for h. influenzae meningitis. Caused by meningococcus or pneumococcal meningitis, when patients should not be used, this product is also available. Topical treatment of trachoma or purulent bacteria infection
Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations,
although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, chloramphenicol is still widely used because it is
exceedingly inexpensive and readily available.
Chloramphenicol is used for the treatment of serious infections when the microorganism is resistant to less toxic antibiotics and also when its ability to penetrate to the site of the infection is superior to less toxic alternative antibiotics.
Chloramphenicol is used only when safer drugs are contraindicated; pregnancy,lactation,or known hypersensitivity to this drug also prohibits its use.
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