Pharmaceutical Intermediate Diltiazem HCl Purity Diltiazem Powder Material Hydrochloride Diltiazem

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Dsung-Diltiazem
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Diltiazem
• Name: Diltiazem Powder
• Appearance: White Crystalline Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediate
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 42399-41-7
• Mf: C22h26n2o4s
• MW: 414.51784
• Density: 1.26
• Melting Point: 187-188 C
• Boiling Point: 594.4 C at 760 Mmhg
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 5 Ton/Month

Product Description

Pharmaceutical Intermediate Diltiazem Hcl Purity Diltiazem Powder Material Hydrochloride Diltiazem

 

Product Description

Product Details

Product Name	Diltiazem
CAS No.	42399-41-7
MF	C22H26N2O4S
MW	414.51784
Appearance and shape	White crystalline powder

Diltiazem is a nondihydropyridines calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.Diltiazem relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure. Additionally, it lowers blood pressure by acting on the heart itself to reduce the rate,strength, and conduction speed of each beat.

Application & Function

Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.Chemically, it is based upon a 1,4-thiazepine ring, making it a benzothiazepine-type calcium channel blocker.
It is a vasodilator of coronary and peripheral vessels, which reduces peripheral resistance and afterload, though not as potent as the dihydropyridine (DHP) calcium channel blockers. This results in minimal reflexive sympathetic changes.
Diltiazem has negative inotropic, chronotropic, and dromotropic effects. This means diltiazem causes a decrease in heart muscle contractility - how strong the beat is, lowering of heart rate - due to slowing of the sinoatrial node, and a slowing of conduction through the atrioventricular node - increasing the time needed for each beat. Each of these effects results in reduced oxygen consumption by the heart, reducing angina symptoms. These effects also reduce blood pressure by causing less blood to be pumped out.

Specification