Protecting Liver Deoxycholate Sodium Pharmaceutical Grade Deoxycholate Sodium
Product Description
Product Details
| Product Name |
Deoxycholate Sodium |
| Appearance |
White Powder |
| CAS No. |
302-95-4 |
| MF |
C24h39nao4 |
| MW |
414.562 |
Deoxycholate Sodium is a sodium salt of deoxycholic acid. At room temperature, it is a white crystalline powder with a bili-like odor and a strong bitter taste. Sodium deoxycholate is an ionic stain remover that can be used to lyse cells and dissolve water-insoluble proteins. It can also be used in biliolytic experiments. The principle is that bile or bile salts have surface activity, which can quickly activate autolysin and accelerate the self-dissolution of bacteria such as Streptococcus pneumoniae.
Sodium deoxycholate can be used in biochemical research. The bacterial medium was prepared to replace the cerebrin for cholesterol flocculation test. Protein analysis; It can be used for the extraction of membrane receptors and other plasma membrane proteins and for the separation of nuclei.
Application&Function
(1) Historically sodium deoxycholate was used as an intermediate for the production of corticosteroids, which have anti-inflammatory indications.
(2) It is used in the preparation and formulation of certain microbiological diagnostic media.
(3) An emerging use of sodium deoxycholate acid is as a biological detergent to lyse cells and solubilise cellular and membrane components.
(4) Popular anionic, bile-acid detergent for many laboratory uses
(5) Effective in disrupting and dissociating many types of protein interaction
(6) Useful for elution or regeneration of certain kinds of affinity columns
(7) It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer), but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement.
Specification
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