| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 140/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Product Name | Cefixime |
| Appearance | White Powder |
| CAS | 79350-37-1 |
| WF | C16h15n5o7s2 |
| MW | 453.45000 |
Cefoxime, also known as cefotaxime cephalosporin, cefoperazone, or cefuroxime, belongs to the third generation of oral cephalosporin antibiotics. It has a wide antibacterial spectrum and has certain antibacterial effects on some Gram negative and Gram positive bacteria. The main mechanism is to inhibit the synthesis of bacterial cell walls, which can exert bactericidal effects. Dispersible tablets refer to tablets that can quickly disintegrate and evenly disperse in water, and have the characteristics of convenient administration, rapid disintegration, fast absorption, and high bioavailability. Therefore, cefuroxime dispersible tablets absorb cefuroxime faster than capsule and tablet forms. The antibacterial mechanism of cefuroxime is similar to that of other third-generation cephalosporins, by binding to one or more penicillin binding proteins (PBPs) to inhibit cell wall synthesis during bacterial cell division. PBPs are located on the cytoplasmic membrane of bacteria and may be catalytic enzymes in the late stage of bacterial cell wall synthesis. The effect of this product is to cause bacteria to form defective cell walls that are unstable to osmotic pressure, thereby exerting antibacterial effects. Different strains have their own unique PBPs. The different affinities of cefuroxime for different PBPs are the main factors affecting its antibacterial spectrum activity. Drug interactions
The third-generation oral cephalosporin broad-spectrum antibiotics have strong antibacterial effects on gram-positive bacteria such as Streptococcus, Neisseria gonorrhoeae, influenza bacteria, as well as resistant Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis to cefaclor, cefoxil, and cefoperazone. They also stabilize β - lactases produced by various bacteria. Long acting and efficient, can be administered once a day. Clinically used for respiratory tract infections, urethral infections, biliary tract infections, etc. caused by sensitive bacteria
Clinically, it is used to treat bacterial infectious diseases caused by Streptococcus (except enterococcus), Streptococcus pneumoniae, Neisseria gonorrhoeae, Escherichia coli, Blahanococcus catarrhalis, Serratia, Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Haemophilus influenzae, Klebsiella, Serratia, Proteus and Influenza. The indications are as follows:
1. Respiratory system infections, such as pneumonia, tonsillitis, pharyngitis, bronchiectasis (when infected), secondary infections of chronic respiratory system infections, acute and chronic bronchitis, etc.
2. Urinary and reproductive tract infections. Such as gonococcal urethritis, cervicitis, pyelonephritis, cystitis, gonorrhea, etc.
3. Abdominal infections (including cholecystitis, cholangitis, peritonitis).
4. Scarlet fever, otitis media, sinusitis, etc.
){kind=link}