Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Chemical Name | Hydroxychloroquine sulfate |
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Synonyms |
2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol,sulfuric acid; |
CAS No. | 747-36-4 |
Molecular Formula | C18H28ClN3O5S |
Molecular Weight | 433.95000 |
PSA | 131.37000 |
LogP | 4.28400 |
Application
Hydroxychloroquine sulfate is an antimalarial drug, which also has anti-inflammatory, immunomodulatory and anticoagulant effects. At present, hydroxychloroquine is mainly used in the clinical treatment of rheumatoid arthritis, juvenile chronic arthritis, discoid lupus erythematosus and systemic erythema Lupus, but the clinical onset is slower, and usually requires 2 to 4 months of Chemicalbook time. The pharmacological effect of this drug is not very clear. It may be related to stabilizing the lysosomal membrane, inhibiting the formation of prostaglandins, inhibiting the chemotaxis of polymorphonuclear cells and the effect of phagocytic cells, and may interfere with monocyte interleukin- 1. Formation and inhibition of neutrophil superoxide release.