Anti-Tuberculosis CAS 54-85-3 Isoniazid Purity Isoniazid Powder Isoniazid

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-sung Isoniazid
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Product Name: Isoniazid
• Name: Isoniazid Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anti-Tuberculosis
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 54-85-3
• Mf: C6h7n3o
• MW: 137.14
• Density: 1.2620
• Melting Point: 171-173°c
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 1000kg/Month

Product Description

Anti-Tuberculosis CAS 54-85-3 Isoniazid Purity Isoniazid Powder Isoniazid
 

Product Description

Product Details

Product name	Isoniazid
Cas number	54-85-3
Apperance	White powder
MF	C6H7N3O
MW	137.14

Isoniazid is an antibacterial agent used primarily as a tuberculostatic. Target: Antibacterial Isoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH complex. This complex binds tightly to the enoyl-acyl carrier protein reductase known as InhA, thereby blocking the natural enoyl-AcpM substrate and the action of fatty acid synthase. This process inhibits the synthesis of mycolic acid, required for the mycobacterial cell wall. A range of radicals are produced by KatG activation of isoniazid,which has also been shown to be important in the action of another antimycobacterial prodrug PA-824. Isoniazid is bactericidal to rapidly dividing mycobacteria, but is bacteriostatic if the mycobacteria are slow-growing.

Application&Function

1.Antituberculosis inhibits and kills Mycobacterium tuberculosis. Its biomembrane permeability is good. Because of its good curative effect, low toxicity, low cost, and convenience for oral administration, it is listed as the first choice antituberculosis drug.

2.Antidepressant Isoniazid is also the first antidepressant drug, but it exits the market because of its hepatotoxicity.

3.Antibacterial Isoniazid is highly selective for Mycobacterium tuberculosis, strong antibacterial activity, bacteria have bactericidal effect.

Specification