Pharmaceutical Raw Material Ambrisentan 99% Purity Ambrisentan Powder Ambrisentan

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: Dsung-Ambrisentan
• Product Name: Ambrisentan
• Name: Ambrisentan Powder
• Appearance: White or off-White Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediat
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 177036-94-1
• Mf: C22h22n2o4
• MW: 378.42108
• Density: 1.228
• Melting Point: >150 C (DEC.)
• Boiling Point: 551.1 Cat760mmhg
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 2 Ton/Month

Product Description

Pharmaceutical Raw Material Ambrisentan 99% Purity Ambrisentan Powder Ambrisentan

 

Product Description

Product Details

Product Name	Ambrisentan
CAS No.	177036-94-1
MF	C22H22N2O4
MW	378.42108
Appearance and shape	White or off-white powder

Ambrisentan (U.S. trade name Letairis;   E.U. trade name Volibris;   India trade name Pulmonext by MSN labs) is a drug indicated for use in the treatment of pulmonary hypertension.

Application & Function

The peptide endothelin constricts muscles in blood vessels, increasing blood pressure.   Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA).   Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2).  Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), and designated an orphan drug, for the treatment of pulmonary hypertension.

Specification