Raw Material Etravirine Tmc125 Purity 99% Etravirine Powder Pharmaceutical Intermediate Etravirine

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: Dsung-Etravirine
• Product Name: Etravirine
• Appearance: White or off-White Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediate
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 269055-15-4
• Mf: C20h15brn6o
• MW: 435.27700
• Density: 1.57g/cm3
• Melting Point: 265 C (DEC.)
• Boiling Point: 637.4 C at 760mmhg
• Refractive Index: 1.702
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 3 Ton/Month

Product Description

Raw Material Etravirine Tmc125 Purity 99% Etravirine Powder Pharmaceutical Intermediate Etravirine

 

Product Description

Product Details

Product Name	Etravirine
Appearance	White or off-white powder
CAS No.	269055-15-4
MF	C20H15BrN6O
MW	435.27700

Etravirine is a second-generation NNRTI,white to off-white powder,the chemical name is 4-[[6-amino-5-bromo-2 -[(4-cyanophenyl) amino] pyrimidine-4-yl] -oxy]-3, 5-dimethylbenzylnitrile. It was approved by FDA in January 2008 and became one of the important components of highly active antiretroviral therapy (HAART) drugs. It has made great contribution to reduce the incidence and mortality of AIDS.

Application & Function

1.Etravirine is an important component of highly active antiretroviral therapy (HAART).Clinically, it has made great contributions to reducing the incidence and mortality of AIDS.
2.Etravirine can be used in combination with other antiretroviral drugs in adult HIV-1 infected patients who develop resistance after initial treatment with antiretroviral drugs.
3.Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1), which can directly bind to HIV-1 reverse transcriptase and block RNA-dependent and DNA-dependent DNA polymerase activity by destroying the catalytic site of the enzyme.Etraverine does not inhibit human alpha, beta and gamma DNA polymerases.

Specification