Pharmaceutical Intermediate Nilotinib Raw Material Nilotinib Powder Anticancer Nilotinib
Product Description
Product Details
Product Name |
Nilotinib |
CAS NO. |
641571-10-0 |
Purity |
99% |
Melting point |
230-242 C |
Appearance and shape |
White powder |
Nilotinib (Tasigna) is a new type of targeted cancer therapy, which belongs to the tyrosine kinase inhibitor, for the treatment of Gleevec (imatinib) resistant chronic myelogenous leukemia (CML) patients, curative effect.
Nilotinib is a molecular structure of imatinib imatinib improved and has better selectivity to BCR-ABL kinase activity, inhibition of tyrosine kinase compared with imatinib 30 times stronger inhibition on imatinib resistant mutant BCR-ABL kinase activity. It also inhibits the activity of KIT and PDGFR kinase.
Application & Function
A powerful and precise second-generation tyrosine kinase inhibitor, effective in treating patients with drug-resistant or intolerant chronic myelogenous leukemia.
Nilotinib is an antitumor drug, and it is mainly used clinically to treat chronic myelogenous leukemia that is resistant to Gleevec (imatinib).
Specification