| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Adapalene |
| Appearance | White Powder |
| CAS No | 106685-40-9 |
| MF | C28H28O3 |
| MW | 412.52 |
Adapalene is a retinoic acid compound that has been shown to have anti-inflammatory properties in both in vivo and in vitro inflammation models. Its chemical structure is stable and it is not easily decomposed under air and light conditions. The mechanism of action is the same as that of retinoic acid, which can bind to specific retinoic acid nuclear receptors. The difference is that adapalene does not bind to cytoplasmic receptors that bind to proteins. In skin medication experiments conducted in animal models established in mice, it has been demonstrated that adapalene can treat acne and also has effects on acne vulgaris and differentiation processes. The mechanism of action is to reduce the formation of small pimples by promoting normal differentiation of hair cells on hair follicles. In standard anti-inflammatory analyses both in vivo and in vitro, adapalene is more effective than retinoic acid. It can inhibit the chemotactic reactions of human multinucleated white blood cells and suppress the metabolism of multinucleated neutrophils by inhibiting the conversion of arachidonic acid from lipid oxidation to inflammatory mediators, thereby alleviating cell-mediated inflammatory reactions. Suitable for treating common skin acne characterized by acne, papules, and pustules. It can also be used to treat acne on the face, chest, and back.
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