99% Purity CAS 103060-53-3 Daptomycin Antibiotic Daptomycin Powder Material Daptomycin

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Daptomycin
• Product Name: Daptomycin
• Name: Daptomycin Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical;Antibiotic
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 103060-53-3
• Mf: C72h101n17o26
• MW: 1620.693
• Melting Point: 202-204°c
• Density: 1.45
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 500kg/Month

Product Description

99% Purity CAS 103060-53-3 Daptomycin Antibiotic Daptomycin Powder Material Daptomycin

Product Description

Product Details

Product name	Daptomycin
Appearance	Off-white to light yellow powder
CAS NO.	103060-53-3
MF	C72H101N17O26
MW	1620.693
Melting point	202-204°C

Daptomycin is the first entry of a new class of cyclic lipopeptide antibiotics that disrupts multiple aspects of bacterial membrane function including disruption of membrane potential and amino acid transport, inhibition of lipoteichoic acid synthesis and inhibition of peptidoglycan synthesis. It is indicated for the treatment of complicated skin and skinstructure infections (cSSSI) caused by a range of Gram-positive bacteria. This is distinct from previous classes of antibiotics that inhibit bacterial cell wall biosynthesis, bacterial DNA replication, and folate coenzyme biosynthesis. Due to this unique mechanism, cross-resistance has not been noted with any other class of antibiotics.

Application&Function

Daptomycin is from Streptomyces (S.reseosporus) extracted from cyclic lipopeptide antibiotics a new structure of the fermentation broth, it not only has a novel chemical structure, and the mode of action and any one of the approved antibiotics are different: it is through the transport of amino acids disrupt the cell membrane, thus impeding the biosynthesis of bacterial cell wall peptidoglycan, change the nature of cell membrane, can damage the function of bacterial cell membrane in many aspects, and quickly kill gram positive bacteria.

In addition to the role of daptomycin in most clinically relevant gram positive bacteria, it is more important to have in vitro showed methicillin resistant (methicillin) strains, vancomycin and linezolid resistant properties with potent activity for this feature has very important clinical significance in patients with severe infection.

The research shows that the antibacterial spectrum of activity is similar to vancomycin and daptomycin, mainly has a strong antimicrobial effect on Gram positive bacteria, such as Staphylococcus aureus spp MIC=0.125 ~ 0.5 g/ml, the gram bacteria spp MIC=0.06 ~ 0.5 g/ml, 0.25 MIC= of Enterococcus to 2 mu g/ ml. Daptomycin has broad-spectrum antibacterial activity in the gram positive anaerobic bacteria on spp. MIC=0.12, Peptostreptococcus g/ml, spp.MIC=0.5 of Clostridium g/ml of Lactobacillus spp.MIC=1 g/ml.

Specification