Antifungal Antibiotic Nystatin Powder Material Nystatin

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-Sung Nystatin
• Product Name: Nystatin
• Name: Nystatin Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Grade
• Specific: COA
• Test Method: HPLC
• CAS No: 1400-61-9
• MW: 926.0949
• Mf: C47h75no17
• Einecs: 215-749-0
• Melting Point: 160
• Boiling Point: 476
• Transport Package: Negotiabie
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 500kg/Month

Product Description

Antifungal Antibiotic Nystatin Powder Material Nystatin 

 

Product Description

Product Datails

 

CAS	1400-61-9
Appearance	white crystalline powder
Molecular formula	C47H75NO17
Molecular Weight	926.0949

Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida.

Cutaneous, vaginal, mucosal and esophageal Candida infections usually respond well to treatment with nystatin

  Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus. Ergosterol is fairly unique to fungi, so the drug does not have such catastrophic effects on animals.

Application&Function

1. Nystatin is often used as prophylaxis in patients who are at risk for fungal infections, such as AIDS patients with a low CD4+ count and patients receiving chemotherapy.
2. It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.
3. It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.
4. In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.
 

Specification