99% Purity Felodipine Powder Felodipine Material Pharmaceutical Intermediate Felodipine

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung-Felodipine
• Product Name: Felodipine
• Name: Felodipine Powder
• Appearance: White to Light Yellow Powder
• Color: White Color
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Treating Hypertension
• Specific: COA
• Test Method: HPLC UV
• Shelf Life: 2 Years
• CAS No.: 72509-76-3
• Mf: C18h19cl2no4
• MW: 384.26
• Density: 1.277
• Melting Point: 142-145ºC
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 5000kg/Month

Product Description

99% Purity Felodipine Powder Felodipine Material Pharmaceutical Intermediate Felodipine 

Product Description

Product Details

Product name	Felodipine
Appearance	White to light yellow powder
CAS NO.	72509-76-3
MF	C18H19Cl2NO4
MW	384.26

Felodipine is a vasodilatory calcium antagonist with a high degree of vascular selectivity. It is currently indicated for use only in hypertension, either as monotherapy or in conjunction with diuretics or beta blockers
Felodipine is a 1,4-dihydropyridine small molecule antagonist and calcium channel protein inhibitor. Antagonism of the vascular L-type (long-lasting) calcium channel decreases intracellular calcium concentration, softening the tone of vascular tissue and decreasing the peripheral resistance upon the blood stream, effectively decreasing systemic arterial blood pressure without affecting myocardial contractility. Felodipine is described to inhibit cytokine-induced NO and superoxide production as well as cytokine-induced NO synthase (NOS) mRNA induction, and is suggested to act as a scavenger of superoxide and not an inhibitor of inducible NOS induction. This indicates that Felodipine further protects the vasculature against endogenous free radical generation during inflammatory responses.

Application&Function

Used for the treatment of high blood pressure is a selective calcium antagonists, inhibit the main flow of extracellular calcium arterial smooth muscle cells, and selective expansion of small arteries, veins, no such effect, not cause orthostatic hypotension; myocardial also. no significant inhibition. This product reduces renal vascular resistance, while not affect glomerular filtration rate and creatinine clearance rate, renal blood flow did not change even slightly increased, there natriuretic and diuretic effect. It can be used to increase output and cardiac index, significantly reducing afterload, while the systolic function, preload and heart rate had no significant effect.

Specification