| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Colistin |
| Appearance | White Powder |
| CAS No. | 1264-72-8 |
| MF | C53h102n16o17s |
| MW | 2801.27 |
Sulfuric acid colistin belongs to narrow spectrum fungicides. It has strong antibacterial effects on Gram negative bacteria such as Escherichia coli, Salmonella, Pasteurella, Shigella, Brucella, Vibrio, and Pseudomonas aeruginosa. Among them, it has a strong bactericidal effect on Pseudomonas aeruginosa and Vibrio. The bactericidal mechanism is to damage the bacterial cell membrane, increase its permeability, and cause leakage of amino acids, purines, pyrimidines, K+and other substances in the bacterial body. It can also affect nuclear and ribosome function, leading to bacterial death. Bacteria are not easily resistant to this product and have complete cross resistance with polymyxin B. However, there is no cross resistance with other antibiotics. All Gram positive bacteria, Proteus, Brucella, and Serratia are resistant to this product. Sulfuric acid colistin is mainly used to treat intestinal infections caused by Gram negative bacteria, and topically to treat Pseudomonas aeruginosa infections caused by burns and injuries. As a feed drug additive, it has a growth promoting effect.
Characteristics of sulfate colistin
(1) Has strong resistance to Gram negative bacteria. Especially has a specific developmental inhibitory effect on Escherichia coli, Salmonella, and Pseudomonas aeruginosa.
(2) Has the ability to kill bacteria. By inhibiting the selective permeability function of the cell membrane, bacteria die
(3) There is almost no issue of drug resistance. No resistance to factor R was found.
(4) Synergistic effect with anti Gram positive bacteria drugs. When used in combination with zinc bacteriocins, erythromycin, sulfonamides, semi synthetic penicillin, gentamicin, etc., its effect is even better.
(5) No residue. When administered orally, it is almost not absorbed by the intestine, but when injected intramuscularly, blood absorption is good, so there is no need to worry about residues in animal products.
(6) Promote the growth of livestock and poultry, prevent and treat infectious enteritis in livestock and poultry.
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