Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Tacrolimus |
CAS NO. | 104987-11-3 |
Purity | 99% |
Density | 1.19 |
Appearance and shape | White powder |
Tacrolimus, also known as FK506, is a fermentation product isolated from Streptomyces. It is a macrolide antibiotic and a powerful new immunosuppressant, mainly by inhibiting interleukin-2 The release of (IL-2) completely inhibits the effect of T lymphocytes, which is 100 times stronger than cyclosporine (CsA). In recent years, as a first-line drug for liver and kidney transplantation, it has been marketed in 14 countries including Japan and the United States. Clinical experiments show that it has a good effect in transplantation of heart, lung, intestine, bone marrow, etc. At the same time, FK506 also plays an active role in the treatment of atopic dermatitis (AD), systemic lupus erythematosus (SLE), autoimmune eye disease and other autoimmune diseases.