Antibiotic Mupirocin powder Medicine Mupirocin
Product Description
Product Details
| Product Name |
Mupirocin |
| Appearance |
White Powder |
| CAS |
12650-69-0 |
| MF |
C26h44o9 |
| MW |
500.62 |
Mupirocin, also known as Pseudomonas aeruginosa A, is an ideal antibacterial agent for skin surfaces. It was introduced to the market by GlaxoSmithKline in 1985 under the trade name "Bactroban". The US FDA approved the drug for market use in the United States in 1987, and China approved the production and sale of the drug by Sino American Square Pharmaceutical in 1993. Mopirocin is mainly used for the prevention and treatment of skin bacterial infections caused by Gram positive cocci.
The raw material of Baiduobang ointment produced by well-known pharmaceutical company Zhongmei Square in China is mupirocin. This product is a new type of topical antibiotic, which is a metabolite produced in the culture medium of Pseudomonas fluorescens, namely Pseudomonas A. Mainly by reversibly binding to isoleucine transfer RNA synthase, it prevents isoleucine incorporation, terminates protein synthesis of intracellular isoleucine, and leads to bacterial death. It has inhibitory effect at low concentrations and bactericidal effect at high concentrations. Highly sensitive to various gram-positive cocci related to skin infections, especially Staphylococcus (including drug-resistant Staphylococcus aureus) and Streptococcus pyogenes; It is also effective against Listeria monocytogenes and erysipelas erysipelas; It is generally insensitive to gram-negative bacteria, but has certain antibacterial effects on certain gram-negative bacteria such as Escherichia coli, Neisseria spp., Haemophilus influenzae, and Neisseria gonorrhoeae;
Application&Function
Apply antibiotics locally. By reversibly binding to isoleucine transfer RNA synthase, the synthesis of all proteins containing isoleucine in the cell is stopped by preventing isoleucine from entering the human body. Used for acute primary skin bacterial infections such as folliculitis and pustulosis.
It is generally used for inflammation, eczema, and other skin diseases, and is made into the commercially available mupirocin ointment
Mopirocin is mainly used for the prevention and treatment of skin bacterial infections caused by Gram positive cocci, such as primary skin infections such as pustules, boils, folliculitis, as well as secondary skin infections such as eczema, ulcers, and trauma. The main mechanism of the antibacterial effect of mupirocin is to inhibit protein synthesis in bacteria.
Specification
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