Pharmaceutical Intermediate Clotrimazole powder Raw Clotrimazole Powder Material Clotrimazole
Product Description
Product Details
CAS: |
23593-75-1 |
MF: |
C22H17ClN2 |
MW: |
344.84 |
EINECS: |
245-764-8 |
Clotrimazole is a broad-spectrum antifungal drug, with good antibacterial effect on a variety of fungi, especially Candida albicans, whose mechanism of action is to inhibit the synthesis of fungal cell membranes and affect their metabolic processes. It has antibacterial effect on superficial fungi and some deep fungi. It is mainly used for external use in the treatment of cutaneous mycoses, such as ringworm, tinea corporis, ear canal and vaginal mycoses. The product is highly toxic, oral administration may have gastrointestinal reactions, liver function abnormalities and leukopenia, etc.. It is now used sparingly. There is no adverse reaction when used externally, and occasionally there is local inflammation. Topical use has 1%-3% cream, suppositories.
Application&Function
Application
1. Oleanolic acid has the functions of anti-inflammatory, sedative, cardiotonic, diuretic, hypolipidemic, hypoglycemic, protecting liver and reducing enzymes, enhancing immunity and inhibiting the growth of S180 tumor strain.
2. Oleanolic acid has a protective effect on chromosome damage and a preventive effect on experimental atherosclerosis. It is clinically used for the treatment of infectious acute jaundice hepatitis and chronic viral hepatitis.
3. Oleanolic acid has the effect of inhibiting the proliferation of liver fibrosis. In the rats with liver fibrosis treated with oleanolic acid, the hyperplasia of liver fibrosis was severe and significantly alleviated, and the content of hepatic collagen decreased, suggesting that it has the effect of preventing and treating liver cirrhosis.
4. Reducing the level of tyrosine in brain homogenate of liver cirrhosis rats: Because the level of tyrosine in brain homogenate is significantly decreased, it can inhibit the generation of pseudo-neurotransmitters, so it is beneficial to the prevention and treatment of hepatic encephalopathy.
5. Oleanolic acid capsules are non-prescription drugs for liver disease adjuvant drugs, which are used for the adjuvant treatment of acute and chronic hepatitis. It has a certain protective effect on liver damage, can reduce the elevated serum alanine aminotransferase, promote liver cell regeneration, and accelerate the repair of necrotic tissue.
Specification