Raw Material CAS 1051375-16-6 Dolutegravir 99% Purity Dolutegravir Pharmaceutical Intermediate Dolutegravir

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Dolutegravir
• Product Name: Dolutegravir
• Name: Dolutegravir Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical; Anti-Viral
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 1051375-16-6
• Mf: C20h19f2n3o5
• MW: 419.38
• Boiling Point: 668.958 °c at 760 Mmhg
• Density: 1.53
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 500kg/Month

Product Description

Raw Material CAS 1051375-16-6 Dolutegravir 99% Purity Dolutegravir Pharmaceutical Intermediate Dolutegravir

Product Description

Product Details

Product name	Dolutegravir
Appearance	White powder
CAS NO.	1051375-16-6
MF	C20H19F2N3O5
MW	419.38

Dolutegravir (Dolutegravir, Tivicay) is a new anti-AIDS drug developed by the British pharmaceutical giant GlaxoSmithKline (GSK) and Japan's Shionogi Pharmaceutical Company (Shionogi). In July 2012, GlaxoSmithKline Pharmaceuticals and Shionoyoshi Pharmaceuticals announced the results of the Phase III clinical trial of the new AIDS drug Dolutegravir. After receiving dolutegravir and two other old-version AIDS drugs for 48 weeks, 88% of the patients' bodies The virus was successfully suppressed, and Gilead Sciences' three-in-one oral drug Atripla (Efavirenz/Emtricitabine/TenofovirDisoproxilFumarate) After that, 81% of the virus in the patient's body was suppressed. It can be seen that the dolutegravir drug of GlaxoSmithKline is slightly better. According to the researchers, in the comparison trial, due to the side effects of the drug, 10% of the patients eventually stopped taking Gilead's Atripla drug, but only 2% of the patients stopped taking GlaxoSmithKline's dolutegravir. Drugs, it can be seen that the safety of GlaxoSmithKline dolutegravir is slightly higher.

Application&Function

Dulutvir sodium salt is a second-generation HIV-1 integrase chain transfer inhibitor. Dulutvir sodium is currently in phase III clinical trials for the treatment of HIV infection. It has been shown that Dulutvir Chemicalbook sodium salt can effectively inhibit HIV replication in cells infected with inactivated PHIV lentiviral vectors (such as peripheral blood mononuclear cells (PBMC), MT-4 cells and CIP4 cells).

Specification