Raw Material Phenytoin Sodium Tablet Pharmaceutical Grade Phenytoin Sodium Powder Phenytoin Sodium
Product Description
Product Details
| Product Name |
Phenytoin Sodium |
| CAS No. |
630-93-3 |
| Purity |
99% |
| MF |
C15H11N2NaO2 |
| Appearance and shape |
White powder |
Phenytoin is an antiepileptic drug which can be used in the treatment of epilepsy. The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited. Possibly by promoting sodium efflux from neurons, phenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of posttetanic potentiation at synapses. Loss of posttetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas. Phenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic-clonic (grand mal) seizures.
Application & Function
Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer. Target: Sodium Channel Phenytoin sodium is an antiepileptic drug. It is useful to treat partial seizures and generalized tonic-clonic seizures but not primary generalized seizures such as absence seizures or myoclonic seizures. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage-gated sodium channels . Phenytoin has low affinity for resting sodium channels at hyperpolarized membrane potentials .
Specification
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