Anti-Cancer CAS 928326-83-4 Nintedanib Powder Pharmaceutical Grade Nintedanib Antitumor Nintedanib

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-Sung Nintedanib
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Product Name: Nintedanib
• Name: Nintedanib Powder
• Appearance: White Cryatalline Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anthelmintics
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAD No.: 928326-83-4
• Mf: C31h33n5o4
• Boiling Point: 742.199c at 760 Mmhg
• Density: 1.284
• Melting Point: 305c
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 500kg/Month

Product Description

Anti-Cancer CAS 928326-83-4 Nintedanib Powder Pharmaceutical Grade Nintedanib Antitumor Nintedanib

Product Description

Product Details

Product Name	Nintedanib
Appearance	White Cryatalline Powder
CAD No.	928326-83-4
MF	C31H33N5O4

Nintedanib is the first approved drug for the management of idiopathic pulmonary fibrosis (IPF), a rare but often fatal lung disease. Nintedanib is believed to exert its mechanism of action by inhibiting multiple receptor tyrosine kinases, including those that have been implicated in the pathogenesis of IPF (i.e., fibroblast growth factor receptor, platelet-derived growth factor receptor, and vascular endothelial growth factor receptor). Nintedanib also inhibits nonreceptor tyrosine kinases, although the contribution of this inhibition in the efficacy of the drug is unknown.

Application&Function

Nintanib targets platelet-derived growth factor receptors, fibroblast growth factor receptors (FGFR1-3), vascular endothelial growth factor receptors (VEGFR1-3), and the adenosine triphosphate ( ATP) binding sites competitively bind, block the signal pathway of fibrosis process, inhibit the proliferation, metastasis and transformation of fibroblasts, thereby slowing the progression of IPF disease.

Specification