Antimalarial CAS 88495-63-0 Artemether Raw Material Artemether Powder Artemether

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: D-Sung Artemether
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Product Name: Artemether
• Name: Artemether Powder
• Appearance: White Powder
• Color: White
• Store: Cool and Dry
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anthelmintics
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 71963-77-4
• Mf: C16h26o5
• Density: 1.18
• Boiling Point: 358 C
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 500kg/Month

Product Description

Antimalarial CAS 88495-63-0 Artemether Raw Material Artemether Powder Artemether

Product Description

 

Product Details

 

Product name	Artemether
Appearance	White powder
CAS	71963-77-4
MF	C16H26O5

Artemisinin is derivatives are a group of drugs that possess the most rapid action of all current drugs against Plasmodium falciparum malaria.Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P. falciparum malaria. The starting compound artemisinin is isolated from the plant Artemisia annua, sweet wormwood, an herb employed in Chinese traditional medicine.
Chemically, artemisinin is a sesquiterpene lactone containing an unusual peroxide bridge. This peroxide is believed to be responsible for the drug's mechanism of action.
Use of the drug by itself as a monotherapy is explicitly discouraged by the World Health Organization, as there have been signs that malarial parasites are developing resistance to the drug. Therapies that combine artemisinin with some other antimalarial drug are the preferred treatment for malaria and are both effective and well tolerated in patients. The drug is also increasingly being used in Plasmodium vivax malaria,as well as being a topic of research in cancer treatment.

Application&Function

 

Cancer treatment
Artemisinin is undergoing early research and testing for the treatment of cancer.Chinese scientists have shown artemisinin has significant anticancer effects against human hepatoma cells.Artemisinin has a peroxide lactone group in its structure, and it is thought that when the peroxide comes into contact with high iron concentrations (common in cancerous cells), the molecule becomes unstable and releases reactive oxygen species. It has been shown to reduce angiogenesis and the expression of vascular endothelial growth factor in some tissue cultures. Recent pharmacological evidence demonstrates the artemisinin-derivative dihydroartemisinin targets human metastatic melanoma cells with induction of NOXA (phorbol-12-myristate-13-acetate-induced protein 1)-dependent mitochondrial apoptosis that occurs downstream of iron-dependent generation of cytotoxic oxidative stress.

Specification