Pharmaceutical CAS 25316-40-9 Doxorubicin HCl Powder Raw Material Doxorubicin Hydrochloride Powder Medicine Doxorubicin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Dsung-Doxorubicin
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Product Name: Doxorubicin
• Name: Doxorubicin Powder
• Appearance: Oeange-Red Crystalline Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anti-Cancer
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 25316-40-9
• Mf: C27h30clno11
• MW: 579.983
• Melting Point: 216 C
• Boiling Point: 810.3 C at 760 Mmhg
• Flash Point: 443.8 C
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 3 Ton/Month

Product Description

Pharmaceutical CAS 25316-40-9 Doxorubicin Hcl Powder Raw Material Doxorubicin Hydrochloride Powder Medicine Doxorubicin

 

Product Description

Product Details

Product Name	Doxorubicin
CAS No.	25316-40-9
MF	C27H30ClNO11
MW	579.983
Appearance and shape	Oeange-red crystalline powder

Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity.   Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin.   Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis.   Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage.   Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids;   the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

Application & Function

Function
Doxorubicin is an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks.   By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein.
Application
Doxorubicin hydrochloride is a chemotherapy medication used to treat cancer.   This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia.   It is often used together with other chemotherapy agents.

Specification