Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Powder |
Purity: | >99% |
Samples: |
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Customization: |
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Product Name | Nilotinib |
CAS No. | 641571-10-0 |
MF | C28H22F3N7O |
MW | 529.527 |
Appearance and shape | White to off-white powder |
Function:
Nilotinib (Tasigna) is a new type of targeted cancer therapy, which belongs to the tyrosine kinase inhibitor, for the treatment of Gleevec (imatinib) resistant chronic myelogenous leukemia (CML) patients, curative effect.
Nilotinib is a molecular structure of imatinib imatinib improved and has better selectivity to BCR-ABL kinase activity, inhibition of tyrosine kinase compared with imatinib 30 times stronger inhibition on imatinib resistant mutant BCR-ABL kinase activity. It also inhibits the activity of KIT and PDGFR kinase.
Application:
A powerful and precise second-generation tyrosine kinase inhibitor, effective in treating patients with drug-resistant or intolerant chronic myelogenous leukemia.
Nilotinib is an antitumor drug, and it is mainly used clinically to treat chronic myelogenous leukemia that is resistant to Gleevec (imatinib).
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