Pharmaceutical Intermediate Amphotericin B Antibiotic Raw Material Amphotericin B Powder Amphotericin B

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: Dsung-Amphotericin B
• Product Name: Amphotericin B
• Name: Amphotericin B Powder
• Appearance: Yellow Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediate
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 1397-89-3
• Mf: C47h73no17
• MW: 924.08
• Density: 1.34
• Melting Point: >170 C
• Boiling Point: 804.34 C (Rough Estimate)
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 5 Ton/Month

Product Description

Pharmaceutical Intermediate Amphotericin B Antibiotic Raw Material Amphotericin B Powder Amphotericin B

 

Product Description

Product Details

Product Name	Amphotericin B
CAS No.	1397-89-3
MF	C47H73NO17
MW	924.08
Appearance and shape	Yellow powder

Amphotericin B, also known as Lushanmycin, is a polyene antifungal antibiotic isolated from the culture solution of Streptomyces nodosus. The lushanmycin is the same substance, and has significant effects on Cryptococcus neoformans, Budding yeast dermatitis, Budding brasiliensis, Histoplasma capsulatum, Sp. schenckii, Candida albicans and several Nocardia species. Chemicalbook bacteriostatic effect. The MIC is generally 0.2 to 0.5 μg/ml. The molecular composition of amphotericin B is a macrolide containing 7 pairs of conjugated double bonds as a ligand and a deoxyhexosaminohexose of trehalosamine (mycosamine) as a sugar group, which are connected by a glycosidic bond. There is an amino group and a carboxyl group in the structure, so it is an amphoteric substance. Appearance is yellow or orange-yellow powder, odorless or almost odorless, tasteless, hygroscopic, easily damaged in sunlight.

Application & Function

Amphotericin B is the first-choice drug for treating deep fungus infection with a broad antifungal spectrum. It has inhibitory effect on cryptococcus, coccidioidomyces immitis, candida albicans, and blastomyces with exhibiting bactericidal effect at high concentration, and therefore is a kind of drugs being effective in treating deep fungus infection. Major clinical indications are as follows:
1. It can be used for the treatment of cryptococcosis, North American blastomycosis, disseminated candidiasis, coccidioidomycosis, and histoplasmosis.
2. It can be used for the treatment of mucormycosis caused by the rhizopus genera, absidia, endomycopsis and the basidiobulus sp.
3. It can be used for the treatment of sporotrichum disease caused by schenker sporotrichosis.
4. It can be used for the treatment of aspergillosis caused by the Aspergillus fumigatus.
5. External preparation is suitable for treating chromomycosis, fungal infections infection after burning, respiratory tract candida, Aspergillus or cryptococcus infection, and fungal corneal ulcer.

Specification