Veterinary CAS 1397-89-3 Amphotericin B Antifungal Amphotericin B Powder Raw Amphotericin B

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-Sung Amphotericin B
• Product Name: Amphotericin B
• Name: Amphotericin B Powder
• Appearance: Orange-Yellow
• Color: Orange-Yellow
• Grade: Veterinary
• Assay: HPLC 99%
• Application: Antifungal
• Specific: COA
• Test Method: HPLC
• CAS No: 1397-89-3
• Mf: C47h73no17
• MW: 924.08
• Einecs: 215-742-2
• Density: 1.34
• Hc: 29419090
• Transport Package: Negotiabie
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 500kg/Month

Product Description

Veterinary CAS 1397-89-3 Amphotericin B Antifungal Amphotericin B powder Raw Amphotericin B

Product Description

Product Datails

product name	Amphotericin B
cas number	1397-89-3
apperance	White powder
Density	1.3±0.1 g/cm3
MF	C47H73NO17
MW	924.079

Amphotericin B is a polyene antifungal drug. Fungi that are sensitive to this product include Cryptococcus neoformans, Blastomyces dermatitis, Histoplasma, Coccidioides, Sporothrix, Candida, etc. Some Aspergillus species are resistant to this product; skin and Trichophyton Most of them are resistant. This product has no antimicrobial activity against bacteria, rickettsiae, viruses, etc. The drug concentration achieved by the commonly used therapeutic dose has only bacteriostatic effect on fungi.

Application&Function

Amphotericin B (Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec) is a polyene antifungal drug, often used intravenously for systemic fungal infections. It was originally extracted from Streptomyces nodosus, a filamentousbacterium, in 1955 at the Squibb Institute for Medical Research from cultures of an undescribed streptomycete isolated from the soil collected in the Orinoco River region of Venezuela. Its name originates from the chemical's amphoteric properties. Two amphotericins, amphotericin A and amphotericin B are known, but only B is used clinically, because it is significantly more activein vivo. Amphotericin A is almost identical to amphotericin B (having a double C=C bond between the 27th and 28th carbons), but has little antifungal activity.

Currently, the drug is available as plain amphotericin B, as a cholesteryl sulfate complex (ABCD), as a lipid complex (ABLC), and as a liposomal formulation (LAmB). The latter formulations have been developed to improve tolerability for the patient, but may show considerably different pharmacokinetic characteristics compared to plain amphotericin B.

Specification