• Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole
  • Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole
  • Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole
  • Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole
  • Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole
  • Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole

Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole

Powder: Yes
Customized: Customized
Certification: GMP, HSE, ISO 9001, USP, BP
Suitable for: Elderly, Children, Adult
State: Powder
Purity: >99%
Samples:
US$ 185/kg 1 kg(Min.Order)
| Request Sample
Customization:
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  • Overview
  • Product Description
  • Product Datails
  • Application&Function
  • Specification
Overview

Basic Info.

Model NO.
D-sung-Itraconazole
Product Name
Itraconazole
Name
Itraconazole Powder
Appearance
White Powder
Color
White Color
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical Grade
Specific
COA
Test Method
HPLC UV
CAS No
84625-61-6
MW
705
Mf
C35h38cl2n8o4
Density
1.4
Melting Point
850
Boiling Point
166
Transport Package
Negotiable
Specification
99%
Trademark
D-Sung
Origin
Xi′an Shaanxi
Production Capacity
5000kg/Month

Product Description

Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole
Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole 
Product Description

Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole

Product Datails

Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole

Product Name Itraconazole
Synonyms Itraconazole
MW 705.63
Mol File 84625-61-6.mol
Product Categories pharmaceutical intermediate
Appearance powder 

Itraconazole is an artificially synthetic clotrimazole, being a broad-spectrum synthetic antifungal agent. Its antimicrobial spectrum and antimicrobial mechanism is similar to clotrimazole, but has strong antibacterial activity against Aspergillus.
It exerts its anti-fungal effect through changing the fungal cell membrane permeability with antibacterial activity against superficial and deep fungal pathogens. Its antibacterial spectrum is broader and stronger than ketoconazole, being able to inhibit the ergosterol synthesis of fungal cell membrane, thus playing the antifungal effect.
This product is suitable for the treatment of Dermatophytes (Trichophyton, Microsporum, Flocculent Epidermophyton), Yeast [Cryptococcus neoformans, Pityrosporum, Candida (including Candida albicans, Candida glabrata and candida krusei)], Aspergillus, Histoplasma, Paracoccidioides brasiliensis, Sporothrix schenckii, Hormodendrum, Cladosporium, Blastomyces dermatitidis and various kinds of other types of yeasts and fungi. Itraconazole is not able to inhibit the growth of Rhizopus and Mucor.

Application&Function

Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole

1) Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus which fluconazole is not.
2) It is also prescribed for systemic infections, such as aspergillosis, candidiasis, and cryptococcosis
3) Itraconazole has also recently been explored as an anticancer agent for patients with basal cell carcinoma.
The im idazole antifungal agents for the triazole ring, through inhibiting the activation of cytochrome P-450, including oxidase and peroxidase, disable the 14, alpha-methyl sterols to be dehydrogenated and be converted to ergosterol, so that the growth and proliferation of fungi are inhibited. They have strong lipophilicity and penetrate through the biofilm to inhibit the binding of the membrane to the fungus.
The antibacterial spectrum is similar to ketoconazole. It is effective in the treatment of superficial fungal diseases such as vaginal and oral candidiasis as well as skin mycosis. Furthermore, it is expected to become the highly-efficient and safe drugs for the treatment of deep fungal infections such as cryptococcal encephalitis (AIDS). It is used for the treatment of vulvovaginal candidiasis, pityriasis and skin fungal disease pityriasis caused by sensitive fungi.
It can be used for the synthesis of broad-spectrum a zole antifungal agents for the treatment of systemic infection caused by deep fungus. It can also be used for the treatment of candidiasis and aspergillosis.
It is used for the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis.
It is anti Fungal and used in the treatment of stomach upset/ indigestion and other gastrointestinal conditions.

Specification

Antifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material ItraconazoleAntifungal Itraconazole Powder Pharmaceutical Itraconazole Powder Material Itraconazole


 

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Management System Certification
ISO 9001, ISO 14001, GMP, HACCP