| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product name | Phenolphthalein |
| Cas number | 77-09-8 |
| Apperance | White Powder |
| MF | C20H14O4 |
| MW | 318.32276 |
Pharmacological effects
Phenolphthalein irritating laxatives, the main role in the large intestine. After oral administration in the intestinal alkaline environment to
form soluble sodium salt, stimulate the plexus wall plexus, a direct role in the intestinal smooth muscle, so that peristalsis increased.
At the same time phenolphthalein and inhibit intestinal absorption of water, so that water and electrolyte accumulation in the colon,
resulting laxation effect. The role of strength and intestinal size of alkaline, and its role in mild, rarely cause intestinal spasm.
Pharmacokinetics
Phenolphthalein after oral 6 ~ 8h effect. About 15% of oral absorption after absorption of drugs mainly in the form of glucuronide by the
kidneys or excretion of excreted, some can also be excreted to the intestine by the bile, was reabsorbed in the intestine to form enterohepatic
circulation, thereby prolonging the duration of action , So the role of a single administration of sustainable 3 to 4 days. Unabsorbed part is
excreted via feces. Phenolphthalein can also be secreted by milk.
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