| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Coluracetam |
| Appearance | White Powder |
| CAS No. | 135463-81-9 |
| MF | C19H23N3O3 |
| MW | 341.4 |
Main Functions:
•Brain Optimization: Coluracetam is a choline uptake enhancer which boosts the effects of choline in your brain. It increases the production of acetylcholine (ACh) through HACU. Resulting in better learning and memory.[i]
•Neurotransmitters: Coluracetam desensitizes glutamate (AMPA) receptors in your brain.[ii] Which boosts neural signaling by increasing the effectiveness of glutamate. Resulting in better focus and concentration.
•Mood & Anti-anxiety: Coluracetam is effective in treating anxiety and depression. Even in people suffering from major depression and who do not respond to SSRI's.
Application:
1) Memory and Learning
Coluracetam improved memory and learning in rats treated with a nerve toxin that damages the choline uptake system in the brain. This improvement surprisingly lasted beyond treatment. However, these benefits in learning and memory were not seen in rats who were not exposed to the nerve toxin.
Acetylcholine levels are often lower in those with Alzheimer's. By boosting acetylcholine in the hippocampus, coluracetam may improve some Alzheimer's symptoms, such as poor memory and learning.
In rats that were given the recreational drug (which inhibits ChAT, the enzyme that creates acetylcholine), coluracetam repaired the damage to the learning function by increasing ChAT.
2) Anxiet
In a rat study, dosing 21 days of coluracetam led to a 20% improvement in anxiety, which was greater than the 12% effect had in a single dose in the same study.
3) Schizophrenia
The enzyme that helps make acetylcholine (ChAT) is impaired in schizophrenia.
Coluracetam increased the activity of ChAT in rats with nerve cell damage. More research directly on people with schizophrenia is needed.
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