Pharmaceutical Grade Chloroquine Phosphate Antimalarial Chloroquine Phosphate Powder Chloroquine Phosphate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Dsung-Chloroquine Phosphate
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Product Name: Chloroquine Phosphate
• Name: Chloroquine Phosphate Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Antimalarial
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 50-63-5
• Molecular Formu: C18h32cln3o8p2
• Boiling Point: 460.6
• Melting Point: 200
• Molecular Weight: 515.865
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaaxi
• Production Capacity: 500kg/Month

Product Description

Pharmaceutical Grade Chloroquine Phosphate Antimalarial Chloroquine Phosphate Powder Chloroquine Phosphate

Product Details

Product Name	Chloroquine Phosphate
CAS NO.	50-63-5
Purity	99%
Grade Standard	Pharmaceutical Grade
MF	C18H32ClN3O8P2
Molecular weight	515.865

 

 

Chloroquine diphosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.

Application&Function

 

Malaria
Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae. After the malaria parasite Plasmodium falciparum started to develop widespread resistance to it.
Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations.
Amebiasis
In treatment of amoebic liver abscess, chloroquine may be used instead of or in addition to other medications in the event of failure of improvement with metronidazole or another nitroimidazole within 5 days or intolerance to metronidazole or a nitroimidazole.
Rheumatic disease
As it mildly suppresses the immune system, it is used in some autoimmune disorders, such as rheumatoid arthritis and lupus erythematosus.

Specification