99% Purity Promestriene Powder Raw Material Promestriene Powder Pharmaceutical Promestriene

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung-Promestriene
• Product Name: Promestriene
• Name: Promestriene Powder
• Appearance: White Powder
• Color: White Color
• Grade: Pharmaceutical Grade
• Specific: COA
• Test Method: HPLC UV
• Application: Pharmaceutical Grade
• CAS No: 39219-28-8
• Mf: C22h32o2
• MW: 328.496
• Einecs: 254-361-6
• Hc: 29093090
• Density: 1.06
• Melting Point: 64
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 5000kg/Month

Product Description

99% Purity Promestriene powder Raw Material Promestriene powder Pharmaceutical Promestriene

Product Description

Product Datails

Product name	Promestriene
CAS	39219-28-8
Molecular formula	C22H32O2
Molecular weight	328.49
Melting point	64

Promestriene (INN) (brand names Colpotrofin, Colpotrophine, Delipoderm), also known as estradiol 3-propyl 17β-methyl diether, is a synthetic, steroidal estrogen used topically in a 1% cream formulation. It is the 3-propyl and 17β-methyl diether of estradiol.The drug is described as a tropic agent and antiseborrheic. It has not been found to be effective in the treatment of androgenic alopecia or other conditions of cutaneous androgenization.

Application&Function

Promestriene is a kind of special estradiol diether with its special molecular structure making it cause the biological effects in situ without the necessity of exerting the effect after being metabolized. It has a biological half-life of being smaller than 24 h. Therefore, upon vaginal administration, drug will directly take effect on the vaginal mucosa without being absorbed by the mucosa. There is no accumulation of estrogen in the body, particularly in the estrogen-sensitive organs far away from the vagina. Clinical observation further noted that the topical administration of promestriene has no effect on the plasma sex hormone binding globulin (SHBG), estrone (E1), estradiol (E2), estriol (E3), LH and FSH, and can effectively prevent and treat the atrophic vaginitis with strict local estrogen effect. 

Specification