Antiviral Valacyclovir HCl Powder Pharmaceutical Grade Valacyclovir Hydrochloride Raw Material Valacyclovir HCl

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung-Valacyclovir Hcl
• Product Name: Valacyclovir
• Name: Valacyclovir Powder
• Appearance: White Powder
• Color: White Color
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anti-Viral
• Specific: COA
• Test Method: HPLC UV
• CAS: 124832-27-5
• Mf: C13h21cln6o4
• MW: 360.8
• Density: 1.55
• Melting Point: 170-172c
• Boiling Point: 588.4c at 760 Mmhg
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Xi′an Shaanxi
• Production Capacity: 5000kg/Month

Product Description

Antiviral Valacyclovir Hcl powder Pharmaceutical grade Valacyclovir Hydrochloride Raw Material Valacyclovir Hcl

Product Description

Product Datails

Product Name	Valacyclovir
CAS	124832-27-5
Appearance	White crystalline powder
MF	C13H21ClN6O4
MW	360.8
Purity	99%
Shelf Life	2 Years

Valacyclovir hydrochloride, an orally active L-valyl ester of the potent antiviral agent aciclovir, was launched in 1995 in the United Kingdom for the treatment of herpes simplex virus (HSV) infections of the skin and mucous membranes, including initial and recurrent enital herpes. As a prodrug, valaciclovir has an improved pharmacokinetic profile to aciclovir. It is rapidly absorbed after oral administration and extensively converted to aciclovir via first-pass metabolism to achieve plasma levels of aciclovir comparable to those seen with aciclovir via i.v. route. Valacyclovir is then activated selectively in virus-infected cells by viral thymidine kinase to form aciclovir triphosphate in a stepwise fashion. This active species inhibits viral DNA polymerase via irreversible binding to the active site of the enzyme. Once aciclovir is incorporated into the elongating viral DNA, it terminates replication of the viral DNA strand, an antiviral mechanism unique to aciclovir. Valacyclovir is reportedly in clinical trials for the suppression of cytomegalovirus infection and disease in renal transplant patients.

Application&Function

Treatment of initial episodes of genital herpes in immunocompetent or HIV-infected adults and adolescents.
Treatment of herpes labialis (perioral herpes, cold sores, fever blisters) in adults and adolescents.
Treatment of recurrent mucocutaneous HSV infections in HIV-infected adults.
Valaciclovir hydrochloride hydrate is the l-valine ester of acyclovir, which is the body prodrug of acyclovir. Acyclovir is hydrolyzed into acyclovir immediately after entering the body. It is used for the treatment of varicella zoster and herpes simplex virus type I and II infection, including incipient and recurrent genital herpes virus infection.

Specification