Pharmaceutical Intermediate Antipyrine Raw Material Antipyrine Powder Purity Antipyrine

• Powder: Powder
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Antipyrine
• Product Name: Antipyrine
• Name: Antipyrine Powder
• Appearance: White Powde
• Color: White
• Specific: COA
• Grade: Pharmaceutical Grade
• Assay: 99%
• Application: Pharmaceutical
• Test Method: HPLC Tlc
• CAS: 60-80-0
• Mf: C11h12n2o
• MW: 188.23
• Melting Point: 109-111
• Boiling Point: 319
• Shelf Life: 2 Years
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 1000kg/Month

Product Description

Pharmaceutical Intermediate Antipyrine Raw Material Antipyrine Powder Purity Antipyrine

Product Description

Product Details

Product Name	Antipyrine
CAS No.	60-80-0
MF	C11H12N2O
MW	188.23
Appearance and shape	White crystalline powder

Antipyrine is an antipyretic and analgesic drug, a non-steroidal anti-inflammatory drug and an antipyretic. It has strong antipyretic, analgesic, anti-inflammatory and anti rheumatic effects. It is colorless crystal or white crystalline powder. Soluble in benzene, ethanol, water, chlorofor, slightly soluble in ether. Odorless, slightly bitter.It was first synthesized by Ludwig Knorr in 1883. It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochlori acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganat oxidizes it to pyridazine tetracarboxylic acid. Phenazone has an elimination half life of about 12 hours.

Application&Function

Function:
Antipyrine, as an antipyretic, analgesic and anti-inflammatory drug pyrazolone, inhibits the synthesis and release of prostaglandin E1 in the anterior hypothalamic neurons, and restores the normal response and antipyretic effect of temperature regulating central sensory neurons; Amidopyrine also inhibits the synthesis and release of prostaglandins in local tissue inflammation, stabilizes lysosomal membrane, affects the phagocytosis of phagocytes, and has anti-inflammatory effect.
Application:
Antipyretic analgesic, used for fever, headache, joint pain, neuralgia, dysmenorrhea and active rheumatism. Aminopyrine is a pyrazolone non steroidal anti-inflammatory drug with strong antipyretic, analgesic, anti-inflammatory and anti rheumatic effects. However, due to serious adverse reactions, such as agranulocytosis, aplastic chemicalbook anemia and so on. Therefore, its clinical application has been decreasing and gradually tends to be eliminated. Aminopyrine can also be used as analytical reagent to determine antimony, bismuth, cobalt, ketone, cyanide, gold, iron iodate, lead, nickel, nitrite, osmium, oxides of nitrogen, palladium, platinum, silver and zinc.

Specification