Raw Material Taxol powder Extract Taxol powder Taxol
Product Description
Product Details
Product Name |
Taxol |
CAS |
33069-62-4 |
Appearance |
White crystalline powder |
MF |
C47H51NO14 |
MW |
853.92 |
Purity |
99% |
Shelf Life |
2 Years |
Taxol is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to Taxol and the BMS compound is sold under the trademark 'Paclitaxel'. In this formulation, Taxol is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which Taxol is bound to albumin, is sold under the trademark Abraxane.
Application&Function
Function
1. Paclitaxe is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxe has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.
Specification