Raw Material Clotrimazole powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole
Product Description
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
Product Datails
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
Product Name: |
Clotrimazole |
CAS |
23593-75-1 |
WF |
C22H17ClN2 |
MW |
344.83678 |
density |
1.13 |
Clotrimazole is an imida derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl dye RH421 that has been widely used to study the transport mechanism of P-type ATPases.
Application&Function
Clotrimazole is commonly available as an over-the-counter substace in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops. Fungal infections can be slow to clear up, so the usual course for an anti-fungal agent is, in general, longer than the typical 3-7 days of an antibiotic. Clotrimazole is also commonly found in conjunction , known as Lotriderm, to add steroid properties. Additionally, Clotrimazole is used to treat the sickling of cells (related to sickle cell anemia) by blocking ion channels in the RBC (red blood cell) membrane, keeping ions and water within the cell.
Specification
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)
![Raw Material Clotrimazole Powder Antifungal Clotrimazole Powder Raw Powder Clotrimazole](//www.micstatic.com/athena/img/transparent.png)