Raw Material CAS 132203-70-4 Cilnidipine API Cilnidipine Powder Pharmaceutical Intermediate Cilnidipine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Dsung-Cilnidipine
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Product Name: Cilnidipine
• Appearance: Yellow Crystalline Powder
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Pharmaceutical Intermediate
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 132203-70-4
• Mf: C27h28n2o7
• MW: 492.52042
• Density: 1.24
• Melting Point: 97-99 C
• Boiling Point: 652.6 Cat760mmhg
• Refractive Index: 1.581
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-Sung
• Origin: Shaanxi
• Production Capacity: 4 Ton/Month

Product Description

Raw Material CAS 132203-70-4 Cilnidipine API Cilnidipine Powder Pharmaceutical Intermediate Cilnidipine

 

Product Description

Product Details

Product Name	Cilnidipine
Appearance	Yellow crystalline powder
CAS No.	132203-70-4
MF	C27H28N2O7
MW	492.52042

Clinidipine is a kind of calcium channel blocker.It is a kind of novel calcium antagonist with the blocking effect on both L-type and N-type calcium channels.It is mainly used for the treatment of hypertension.Based on its effect on both N-type and L-type calcium channel, it can dilate both arterioles and venules, further reducing the pressure in the capillary bed.In addition, cilinidipine can attenuate the platelet activation associated with catecholamines.
Cilnidipine is a dihydropyridine calcium antagonist introduced for the treatment of essential and severe hypertension and hypertension associated with renopathy.Cilnidipine has been demonstrated to exert a potent vasodilating effect by blocking calcium influx via dihydropyridine-sensitive, voltage-dependent calcium channels.Compared to nifedipine and nicardipine, cilnidipine is superior, especially for long-term treatment, due to its characteristics of slow onset and long duration with less cardiodepressant activity.

Application & Function

1.   Cilnidipine decreases blood pressure and is used to treat hypertension and its comorbidities.
2.   Due to its blocking action at the N-type and L-type calcium channel, cilnidipine dilates both arterioles and venules, reducing the pressure in the capillary bed.
3.   Cilnidipine is vasoselective and has a weak direct dromotropic effect, a strong vasodepressor effect, and an arrhythmia-inhibiting effect.
4.   Blood pressure control with cilnidipine treatment in Japanese post-stroke hypertensive patients.
5.   The Ambulatory Blood Pressure Control and Home Blood Pressure.

Specification