Nootropics Nefiracetam Powder Nefiracetam
Product Description
Product Details
| Product Name |
Nefiracetam |
| Appearance |
White Powder |
| CAS No. |
77191-36-7 |
| MF |
C14h18n2o2 |
| MW |
246.31 |
Nefiracetam is a nootropic of the racetam family.Nefiracetam is cognitive enhancer with an IC50 of approximately 150-200 μM for Ro 5-4864. This compound activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems.Nefiracetam displays potent neuroprotective action in the retinal ischemia-reperfusion model.
Nefiracetam is a nootropic cognitive enhancer of the racetam family with similarities to Aniracetam.It seems to enhance both GABAergic and cholinergic signalling, and long term usage appears to be both neuroprotective and Nootropic.Nefiracetam's cytoprotective actions are mediated by enhancement of GABAergic, cholinergic, and monoaminergic neuronal systems.
Nefiracetam was derived initially from the parent molecule Piracetam but it shares more structural similarity to Aniracetam.Both nefiracetam and aniracetam are fat soluble racetam compounds used for the purpose of memory enhancement or the treatment of cognitive decline.
Application&Function
The memory mechanisms of nefiracetam seem to be linked back to two pathways.One is prolonging the opening of calcium channels which enhances signalling of a receptor independent of the synapse, and the other pathway seems to be tied into PKC and CAMKII which then augments signalling through cholinergic receptors.The former pathway appears to be critical for long-term potentiation, whereas the latter pathway appears to be vital for neuronal signal enhancement.
Some other minor pathways include being a partial agonist at the glycine binding site of the NDMA receptor (may enhance signalling when there are subpar levels of glycine, but attenuates excessive signalling) and increasing affinity of the muscarinic acetylcholine receptors for its ligand, acetylcholine.
1.Nefiracetam has a function of improving disordered brain function.
2.Nefiracetam is useful for dementia patients.
Specification
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