| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Clascoterone |
| CAS No. | 19608-29-8 |
| MF | C24H34O5 |
| MW | 73.0706 |
| Appearance and shape | White or off-white solid powder |
Clascoterone is the drug for the treatment of hair loss dwindled. It has same function and application with RU58841 and Setipiprant.
Clascoterone is a molecule that acts at the level of the skin, blocking (DHT) from binding to the receptor in the cell. The molecule has a unique mechanism that acts at the skin surface, and is quickly metabolized to free inactive cortexolone, a substance naturally found in the body. The molecule has been evaluated in a variety of animal models as well as initial human trials in Europe. The results of these studies demonstrate that Clascoterone appears to have potent activity without significant local or systemic side effects.
Cortexolone 17α-propionate (developmental code name Clascoterone,CB-03-01), or 11-deoxycortisol 17α-propionate, is a synthetic steroidal antiandrogen-specifically, an androgen receptor antagonist - which is used as a topical medication in the treatment of androgen-dependent conditions including acne vulgaris and androgenic alopecia (male-pattern hair loss). It is the C17α propionate ester of 11-deoxycortisol (cortexolone); C17α esters of 11-deoxycortisol were unexpectedly found to possess antiandrogen activity, and cortexolone 17α-propionate was selected for development based on its optimum drug profile.
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