Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Antipyrine |
CAS No. | 60-80-0 |
MF | C11H12N2O |
MW | 188.23 |
Appearance and shape | White crystalline powder |
Function:
Antipyrine, as an antipyretic, analgesic and anti-inflammatory drug pyrazolone, inhibits the synthesis and release of prostaglandin E1 in the anterior hypothalamic neurons, and restores the normal response and antipyretic effect of temperature regulating central sensory neurons; Amidopyrine also inhibits the synthesis and release of prostaglandins in local tissue inflammation, stabilizes lysosomal membrane, affects the phagocytosis of phagocytes, and has anti-inflammatory effect.
Application:
Antipyretic analgesic, used for fever, headache, joint pain, neuralgia, dysmenorrhea and active rheumatism. Aminopyrine is a pyrazolone non steroidal anti-inflammatory drug with strong antipyretic, analgesic, anti-inflammatory and anti rheumatic effects. However, due to serious adverse reactions, such as agranulocytosis, aplastic chemicalbook anemia and so on. Therefore, its clinical application has been decreasing and gradually tends to be eliminated. Aminopyrine can also be used as analytical reagent to determine antimony, bismuth, cobalt, ketone, cyanide, gold, iron iodate, lead, nickel, nitrite, osmium, oxides of nitrogen, palladium, platinum, silver and zinc.