| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Montelukast |
| Appearance | Off white or white powder |
| CAS No. | 158966-92-8 |
| MF | C35H36ClNO3S |
| MW | 608.16507 |
Function
Montelukastis a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.It blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it.This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.
Application
Montelukast is used for a number of conditions including asthma, exercise induced bronchospasm, allergic rhinitis,primary dysmenorrhoea and urticaria.It is mainly used as a complementary therapy in adults in addition to inhaled corticosteroids, if they alone do not bring the desired effect.It is also used to prevent allergic reactions and asthma flare-ups during the administration of intravenous immunoglobulin.Montelukast is administered as montelukast sodium, with 5.2 mg of montelukast sodium being equivalent to 5 mg of montelukast.
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