| Powder: | Yes |
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| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | Powder |
| Purity: | >99% |
| Samples: |
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| Customization: |
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| Product name | chlorogenic acid |
| Cas number | 327-97-9 |
| Apperance | White Powder |
| MF | C16H18O9 |
Chlorogenic acid has a wide range of biological activities, and modern scientific research on its biological activity has delved into multiple fields such as food, health, medicine, and daily chemical industry. Chlorogenic acid is an important bioactive substance that has antibacterial, antiviral, elevated white blood cells, liver and gallbladder protection, anti-tumor, blood pressure lowering, blood lipid lowering, free radical scavenging, and central nervous system stimulation effects.
Antibacterial and antiviral
Eucommia ulmoides chlorogenic acid has strong antibacterial and anti-inflammatory effects, while aucubin and its polymers have significant antibacterial effects. aucubin has inhibitory effects on both Gram negative and positive bacteria. Peach leaf coral glycoside has antibacterial and diuretic effects, and can promote wound healing; Peach leaf coral glycoside and glucoside can also produce significant antiviral effects after pre cultivation, but they do not have antiviral functions themselves. The Institute of Aging Medical Sciences of Aichi Medical University in Japan has confirmed through research that the alkaline substance extracted from Eucommia ulmoides Oliv. has the function of resisting viruses that damage the human immune system, and this substance may be used to prevent and treat AIDS.
Antioxidant effect
Chlorogenic acid is an effective phenolic antioxidant with stronger antioxidant capacity than caffeic acid, p-hydroxybenzoic acid, ferulic acid, butyric acid, butylhydroxyanisole (BHA), and tocopherol. The reason why chlorogenic acid has antioxidant effect is that it contains a certain amount of R-OH group, which can form hydrogen free radicals with antioxidant effect to eliminate the activity of hydroxyl radical, superoxide anion and other free radicals, so as to protect tissues from oxidative damage.
Eliminating free radicals, anti-aging, and anti-aging of muscles and bones
Chlorogenic acid and its derivatives have stronger free radical scavenging effect than ascorbic acid, caffeic acid and tocopherol (vitamin E), can effectively eliminate DPPH free radicals, hydroxyl radical and superoxide anion free radicals, and can also inhibit the oxidation of low-density lipoprotein. Chlorogenic acid plays an important role in effectively eliminating free radicals in the body, maintaining the normal structure and function of body cells, preventing and delaying the occurrence of tumor mutation and aging. Eucommia ulmoides chlorogenic acid contains a special component that can promote the synthesis and decomposition of collagen in the human skin, bones, and muscles. It has the function of promoting metabolism and preventing decline, and can be used to prevent bone and muscle decline caused by space weightlessness in astronauts. At the same time, it has been found that Eucommia ulmoides chlorogenic acid has a significant anti free radical effect both in vivo and in vitro.
Inhibition of mutations and anti-tumor effects
Modern pharmacological experiments have shown that Eucommia ulmoides chlorogenic acid has anticancer and anti-tumor effects. Japanese scholars have studied the antigenicity inhibitory effect of Eucommia ulmoides chlorogenic acid and found that this effect is related to anti antigenic components such as chlorogenic acid, revealing the important significance of chlorogenic acid in tumor prevention.
Polyphenols in vegetables and fruits such as chlorogenic acid and caffeic acid can inhibit the variability of carcinogen aflatoxin B1 and benzo [a] - pyrene by inhibiting the activation enzyme; Chlorogenic acid can also prevent and fight cancer by reducing the utilization rate of carcinogen and its transport in the liver. Chlorogenic acid has significant inhibitory effects on colorectal cancer, liver cancer, and laryngeal cancer, and is considered an effective chemical protective agent for cancer.
Cardiovascular protective effect
Chlorogenic acid, as a free radical scavenger and antioxidant, has been extensively tested and proven to have a protective effect on the cardiovascular system due to its biological activity. Isochlorogenic acid B has a strong promoting effect on rats. Pre chlorogenic acid B has a strong promoting effect on the release of prostacyclin (PGI2) and anti platelet aggregation in rats; The inhibition rate of antibody induced SRS-A release induced by guinea pig lung debris induction reached 62.3%. Isochlorogenic acid C also promotes the release of PGI2. In addition, isochlorogenic acid B has a strong inhibitory effect on the biosynthesis of thromboxane in platelets and endothelin damage not induced by
Other biological activities
Because chlorogenic acid has a special inhibitory effect on hyaluronidase (HAase) and glucose-6-phosphatase (Gl-6-Pase), chlorogenic acid has certain effects on wound healing, healthy and moist skin, lubrication of joints, prevention of inflammation, and balance regulation of blood sugar in the body.
Chlorogenic acid also has strong inhibitory and killing effects on various diseases and viruses. Chlorogenic acid has pharmacological effects such as lowering blood pressure, anti-bacterial, anti-virus, anti-inflammatory, increasing white blood cells, preventing diabetes, significantly increasing gastrointestinal peristalsis and promoting gastric juice secretion, and has obvious curative effect on acute throat inflammation. Research has shown that oral administration of chlorogenic acid can significantly stimulate the secretion of bile and has the effect of promoting bile and protecting the liver; It can also effectively inhibit the hemolysis of rat red blood cells.
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