Pharmaceutical Intermediates Ribociclib Purity Ribociclib Powder Material Ribociclib

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Powder
• Purity: >99%
• Model NO.: D-sung Ribociclib
• Product Name: Ribociclib
• Name: Ribociclib Powder
• Appearance: White Powder
• Color: White
• Grade: Pharmaceutical Grade
• Assay: HPLC 99%
• Application: Anti-Breast Cancer
• Specific: COA
• Test Method: HPLC
• Shelf Life: 2 Years
• CAS No.: 1211441-98-3
• Mf: C23h30n8o
• MW: 434.548
• Density: 1.39±0.1 g/cm3(Predicted)
• Boiling Point: 730.8±70.0 °c(Predicted)
• Transport Package: Negotiable
• Specification: 99%
• Trademark: D-sung
• Origin: Shaanxi Xi′an
• Production Capacity: 1000kg/Month

Product Description

Pharmaceutical intermediates Ribociclib Purity Ribociclib Powder Material Ribociclib

Product Description

Product Details

Product name	Ribociclib
Appearance	White powder
Cas number	1211441-98-3
MF	C23H30N8O
MW	434.548

Ribociclib is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. Ribociclib specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Ribociclib does not currently have Marketing Authorisation in the EU for any indication. Ribociclib is in phase II studies for breast cancer.

Application&Function

1. A CDK4/6 inhibitor.
2. It inhibits the growth of tumor cells by arresting the cells at the G1 checkpoint, which prevents the tumor cells from proliferating.
3. In the phase III trial, it demonstrating statistically significant improvement in progression-free survival (PFS) compared to letrozol alone at the first pre-planned interim analysis.

Specification